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Breakthrough research shows Vit C kills drug resistant TB

Wed, 22 May 2013 15:56:35 -0400

WASHINGTON - Adding vitamin C to existing tuberculosis drugs regime could shorten the therapy for drug resistant TB, claims new research findings published in the online scientific journal Nature Communications. The striking discovery, by researchers at Albert Einstein College of Medicine of Yeshiva University, has determined that vitamin C kills drug-resistant TB bacteria in laboratory ...

Soligenix ThermoVax technology receives US patent

Thu, 23 May 2013 07:38:45 -0400

Clinical stage biopharmaceutical company Soligenix has received US patent for the vaccine thermostabilization technology, ThermoVax. The patent claims describe methods of preparing an immunologically-active adjuvant-bound, thermostable, freeze dried vaccine composition that uses conventional adjuvants comprised of aluminum salts, in addition to claims covering the adjuvant-bound composition ...

FDA approves entry of R-Tech ophthalmic solution into Phase III trials

Thu, 23 May 2013 07:38:44 -0400

The FDA has approved R-Tech Ueno's novel ophthalmic solution, developed using Novozymes Biopharma's recombinant human albumin, to enter into Phase I/II ...

Study sheds light on the phenomenon of general anesthesia

Thu, 23 May 2013 06:26:50 -0400

brain is a crucial building block for consciousness and that its disruption is associated with unconsciousness when the anesthetics ketamine, propofol or sevoflurane are administered. Brain centers and mechanisms of consciousness have not been well understood, resulting in a need for better monitors of consciousness during anesthesia. In addition, how anesthetics with different structures and ...

European US NSTE-ACS guidelines recommend bivalirudin alone in patients undergoing PCI

Thu, 23 May 2013 05:18:55 -0400

heparin in the absence of GPIIb/IIIa blockade, showing similar 30-day mortality in patients with non-ST segment elevation acute coronary syndromes (NSTE-ACS) undergoing percutaneous coronary intervention (PCI). European and US NSTE-ACS guidelines currently recommend bivalirudin alone as an alternative to unfractionated heparin plus GP IIb/IIIa receptor inhibitors in patients undergoing an ...

Merck releases statement on FDAs Advisory Committee meeting about suvorexant

Thu, 23 May 2013 05:18:55 -0400

Merck (NYSE: MRK), known as MSD outside the United States and Canada, today provided the following statement after the conclusion of the Peripheral and ...

Paediatric Medicines Global Recommendations

Thu, 23 May 2013 05:17:58 -0400

Transparent information on the evidence supporting global recommendations on paediatric medicines should be easily accessible in order to help policy makers decides on what drugs to include in their national drug lists, according to international experts from Ghana and the UK writing in this week's PLOS Medicine. The authors, led by David Sinclair from the Liverpool School of Tropical ...

Corgenix partners with Eli Lilly to develop diagnostic technology

Thu, 23 May 2013 04:10:21 -0400

Corgenix Medical has collaborated with Eli Lilly to develop diagnostic technology that supports the latter's oncology pipeline program. Focused on advancing the proprietary diagnostic technology, originally developed by Lilly, the collaboration agreement is part of Corgenix' expanded contract services business unit for the healthcare and biotechnology industries. Corgenix president ...

Biogen Idec seeks FDA approval for Plegridy in multiple sclerosis therapy

Thu, 23 May 2013 04:10:20 -0400

Biogen Idec is seeking FDA approval for Plegridy (Peginterferon Beta-1a) as multiple sclerosis (MS) medication. The company submitted a biologics license application (BLA) to the FDA for its pegylated subcutaneous injectable candidate developed for relapsing forms of multiple sclerosis. The BLA application included the results from the first year of the two-year Phase 3 ADVANCE study that met ...

GSK US HHS team up to develop drugs against antibiotic resistance and bioterrorism

Thu, 23 May 2013 02:59:30 -0400

GlaxoSmithKline (GSK) has teamed up with Biomedical Advanced Research and Development Authority (BARDA), part of the US Department of Health and Human Services (HHS), to develop drugs against antibiotic resistance and bioterrorism. Development of the new antibiotics will receive funding through a public-private partnership. For the initial period of 18 months, HHS will provide $40m and around ...

Jennerex completes enrollment in Phase 2b trial of liver cancer drug

Thu, 23 May 2013 02:59:29 -0400

Jennerex Biotherapeutics has completed enrolling 120 patients in Phase 2b trial of Pexa-Vec (JX-594, pexastimogene devacirepvec) for the treatment of liver cancer. The TRAVERSE study is designed to assess the efficacy and safety profile of Pexa-Vec against advanced primary liver cancer in patients failing prior therapy with sorafenib. The primary objective is to determine the overall survival ...

Research findings reveal promising new anti-addiction drug

Thu, 23 May 2013 01:50:32 -0400

brain , and identified a compound that blocks cravings for the drug in cocaine-addicted mice. The compound, already proven safe for humans, is undergoing further animal testing in preparation for possible clinical trials in cocaine addicts, the researchers say. "It was remarkably serendipitous that when we learned which brain pathway cocaine acts on, we already knew of a compound, ...

Scientists make important step forward in the quest to develop universal influenza vaccine

Thu, 23 May 2013 01:50:31 -0400

Allergy and Infectious Diseases (NIAID), represents an important step forward in the quest to develop a universal influenza vaccine-one that would protect against most or all influenza strains without the need for an annual vaccination. The scientists designed an experimental vaccine featuring the protein ferritin, which can self-assemble into microscopic pieces ...

Reward offered in Monessen pharmacy robbery

Thu, 23 May 2013 01:27:18 -0400

A $2,500 reward is being offered for information leading to the arrest of the suspect believed to be responsible for a robbery at Union Prescription Center in ...

Judge rules on Medford pharmacy murders lawsuit

Wed, 22 May 2013 21:11:33 -0400

Photo credit: SCPD | David Laffer shot four people to death in Haven Drugs on Father's Day two years ago while robbing the pharmacy of pain pills and muscle relaxants. Laffer is serving life in prison for the murders. (Sept. 23, ...

Powder and Liquid Processing System

Wed, 22 May 2013 16:35:16 -0400

The Ystral Conti-TDS features powder induction, wetting and then dispersing of an agglomerate-free liquid - all with one machine. The patented Conti-TDS system operates dust-free and loss-free. In a single processing unit, it ...

Pharmacy compounding reform bill headed to Senate floor

Wed, 22 May 2013 14:07:21 -0400

A Senate committee passed bipartisan legislation Wednesday that would fundamentally change how large-scale pharmacy compounding is practiced in the ...

Humana to open mail-order pharmacy create 620 jobs in Irving

Wed, 22 May 2013 13:13:36 -0400

Humana plans to open a mail-order pharmacy in August, which is expected to create 620 jobs in Irving. Louisville, Ky.-based health and wellness company Humana Inc. announced Wednesday it plans to open a mail order pharmacy call center and support operation in Irving that is expected to create more than 620 new jobs over the next three years. RightSource, Humana's pharmacy management company, ...

Malvern Instruments To Speak at First PDI Science Workshop on Pharmaceutical Aerosols

Wed, 22 May 2013 12:18:34 -0400

Malvern Instruments and a specialist in particle characterization, is one of a panel of invited speakers at the first Particle Design Industrialization (PDI) Science workshop on Pharmaceutical Aerosols, to be held on June 24-25, 2013 at Hong Kong ...

Bafna Pharmaceuticals recommends 6 dividend for 2012-13

Wed, 22 May 2013 10:00:51 -0400

BAFNAPHARM ), a Chennai-based Pharma company engaged in the manufacturing of pharmaceutical formulations of Betalactum and Non-Betalactum, at its meeting held on May 20, 2013 have recommended ...

Pfizer Announces Plan for Split-Off of Zoetis

Wed, 22 May 2013 09:13:42 -0400

Pfizer Inc. today announced its intention to split off its remaining interest in Zoetis Inc., through an exchange offer. Zoetis, formerly Pfizer's animal health business, completed its initial public offering (IPO) in February 2013. In the exchange offer, Pfizer shareholders can exchange all, some or none of their shares of Pfizer common stock for shares of Zoetis common stock owned by ...

Study New Drug May Help Some Asthmatics

Wed, 22 May 2013 09:13:42 -0400

A new asthma drug being developed by Sanofi and Regeneron Pharmaceuticals may help patients whose condition is not well controlled by existing medicines, according to the results of a small clinical trial released ...

Biogen Submits New MS Drug for FDA Approval

Wed, 22 May 2013 09:13:41 -0400

WESTON, Mass. (AP) -- Biogen Idec has submitted a new injectable multiple sclerosis drug to the Food and Drug Administration for U.S. market ...

iBio announces production of vaccine candidate for new H7N9 influenza virus

Wed, 22 May 2013 09:12:38 -0400

virus by an independent third party laboratory using the iBioLaunch™ platform. This validation milestone was achieved in 21 days as measured from initial antigen sequence information to purification of recombinant protein. The iBioLaunch platform eliminates the need to culture cells under sterile conditions, removes uncertainty about yield consistency for large volumes of production, ...

Antidepressant treatment results in lower rate of MSIMI

Wed, 22 May 2013 09:12:37 -0400

Among patients with stable coronary heart disease and mental stress-induced myocardial ischemia (MSIMI), 6 weeks of treatment with the ...

Study Regardless of pain women are more likely to be prescribed pain-relieving drugs

Wed, 22 May 2013 09:12:37 -0400

Regardless of pain, social class or age, a woman is more likely to be prescribed pain-relieving drugs. A study published in Gaceta Sanitaria (Spanish health scientific journal) affirms that this phenomenon is influenced by socioeconomic inequality between genders in the Autonomous Community in which the patient resides. In 1999, a researcher at the University of Harvard, Ishiro Kawachi, ...

NIH awards $3M grant to UK pharmacy professors firm

Wed, 22 May 2013 07:55:53 -0400

A University of Kentucky pharmacy professors start-up company has been awarded a $3 million grant from the National Institutes of Health to test and market a nasal spray that counteracts opioid overdoses. The Lexington Herald-Leader reports that AntiOp Inc., started by professor Dan Wermeling, will receive the money over three years to continue his work on naloxone. The drug is currently used in ...

New U-M poll shows 1 in 100 parents believe their kids use prescription stimulants to boost grades

Wed, 22 May 2013 06:52:34 -0400

As high schoolers prepare for final exams, teens nationwide may be tempted to use a "study drug" -- a prescription stimulant or amphetamine -- to gain an academic edge. But a new University of Michigan poll shows only one in 100 parents of teens 13-17 years old believes that their teen has used a study drug. Study drugs refer to stimulant medications typically prescribed for the ...

US Organic Group develops over-the-counter organic anti-itch ointment

Wed, 22 May 2013 05:46:33 -0400

Avion unveils Prenate Chewable prenatal vitamin

Wed, 22 May 2013 05:46:32 -0400

Avion Pharmaceuticals has unveiled a chewable, chocolate-flavored version of the Prenate prenatal vitamin family, Prenate Chewable. The new Prenate Chewable leverages taste-masking technology to ensure the patient only experience the Dutch chocolate flavor. Avion sales and marketing vice president Mike Sullivan said, "Choices are beneficial for patients who must take a prenatal vitamin ...

Prostaglandin analogues cause droopy eyelids new study finds

Wed, 22 May 2013 05:45:29 -0400

glaucoma , but their use is not without risks. PGAs have long been associated with blurred vision, dryness, changes in eye color and other side effects. Now a new study has found that these drugs also cause upper and lower eyelid drooping and other issues that can interfere with vision. The findings are described in PLOS ONE. Researchers from the Massachusetts Eye and Ear performed ...

Sanofi Regeneron announce positive Phase 2a study results of asthma drug

Wed, 22 May 2013 03:32:05 -0400

Sanofi and Regeneron Pharmaceuticals have announced positive Phase 2a study results of dupilumab (SAR231893/REGN668) in patients with moderate-to-severe allergic asthma. The study of the IL-4R alpha inhibitor demonstrated 87% reduction in risk of asthma exacerbations in moderate-to-severe asthma patients with elevated eosinophils. Trial lead investigator and the University of Pittsburgh the ...

Experts develop new guidelines for safe and effective use of anticoagulants

Wed, 22 May 2013 03:31:04 -0400

stroke , but they are not without risk, and not just because of their side effects. These high-risk drugs, known as anticoagulants, account for nearly 7 percent of medication errors in hospitalized patients. With health care organizations facing greater pressure to ensure the safe and effective use of anticoagulants, new guidelines have been developed by a panel of health care experts led by ...

Gilead Sciences sofosbuvir MAA gets EMA validation

Wed, 22 May 2013 03:31:04 -0400

Gilead Sciences, Inc. (Nasdaq: GILD) today announced that the company's Marketing Authorisation Application (MAA) for sofosbuvir, a once-daily oral nucleotide analogue inhibitor for the treatment of ...

Cancer Society hits 100 as US cancer rate falls

Wed, 22 May 2013 03:12:36 -0400

NEW YORK (AP) -- The American Cancer Society -- one of the nation's best known and influential health advocacy groups -- is 100 years old this week.Back in 1913 when it was formed, cancer was a lesser threat for most Americans. The biggest killers then were flu, pneumonia, tuberculosis, and stomach bugs. At a time when average life expectancy was 47, few lived long enough to get cancer.But ...

GSK to shut down tablet-packaging facility in Melbourne

Wed, 22 May 2013 02:25:44 -0400

UK-based GlaxoSmithKline (GSK) is planning to shut its tablet-packaging facility in Melbourne, Australia, and thereby axing 120 jobs. The company has planned to shut down the facility as part of a business transformation. The jobs are expected to be axed around the end of 2014 or in 2015. The Melbourne plant is now expected to focus on manufacturing specialized products such as packaging for ...

Study analyzes potential usefulness of new treatment to reopen clogged arteries

Wed, 22 May 2013 02:24:38 -0400

Over the past few decades, scientists have developed many devices that can reopen clogged arteries, including angioplasty balloons and ...